Adrenal fatigue is a term that describes ongoing feelings of fatigue or exhaustion that is not relieved by sleep. The adrenal glands sit on top of the kidneys and are responsible for the secretion of adrenaline, cortisol, DHEA and other hormones that are required to help your body function during times of stress, whether it is physical, emotional or mental. Adrenal fatigue usually occurs after a period of prolonged stress, over work or over training. We use functional pathology to investigate cortisol and DHEA levels. There are different stages of adrenal fatigue, with the most advanced cases being associated with chronic fatigue. Herbal medicine provides the most effective treatment for adrenal fatigue while nutritional support and dietary intervention is also important.